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    Eric Klee, PhD

    Director of Bioinformatics
    Mayo Clinic
    Rochester, Minnesota, United States

    Eric W. Klee, Ph.D., is a consultant-research in the Division of Biomedical Statistics and Informatics, Department of Quantitative Health Sciences, with joint appointments in the Department of Clinical Genomics and in the Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology. He is the Director of Bioinformatics and the Director of the Translational Omics Program, within Mayo Clinic’s Center for Individualized Medicine. Dr. Klee is also the Director of Bioinformatics for the Advanced Diagnostics Laboratory at Mayo Clinic. Dr. Klee holds the academic rank of Associate Professor of Biomedical Informatics, Mayo Clinic College of Medicine. He joined the staff of Mayo Clinic in 2005.
    Dr. Klee’s research focuses on the translational application of -omic technology to advance clinical diagnostics and patient care. He is actively engaged in the development and implementation of systems to support sequence analysis and interpretation of variant information for genetic testing, with a special interest in rare, undiagnosed, Mendelian Disease. Current research includes the use of RNA-sequencing and methyl-sequencing to aid in clinical diagnoses, and anti-sense oligonucleotides as a potential therapeutic strategy for patients. Dr. Klee has authored numerous journal articles, abstracts and other written publications.
    In addition to his research activities, Dr. Klee is active in education, teaching clinical bioinformatics to Department of Laboratory Medicine and Pathology residents and fellows, leading a graduate course on analysis and interpretation of exome and genome data, and co- director of the Discovery Science concentration in the new Masters of AI in Healthcare. He also provides mentorship to medical and predoctoral students and holds full faculty privileges in Clinical and Translational Science at Mayo Graduate School, Mayo Clinic College of Medicine.


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