The potential of cfDNA as a universal, non-invasive biomarker in cancer prognosis, diagnosis, and management of prenatal testing has been shown. To harness the full potential of cfDNA, important considerations should be given to 1) preanalytical stabilization to minimize cfDNA degradation post-sample collection, 2) reliable cfDNA extraction methodology to maximize cfDNA yield with minimal genomic DNA contamination, and 3) appropriate downstream technology with high sensitivity to draw relevant conclusions. We aim to equip researchers with various simple and efficient automated cfDNA extraction workflows. • Get a first-hand look at a new automation platform for nucleic acid extraction • Learn from experts about optimizing cfDNA extraction using liquid handlers and magnetic processors.
