A New Age in Cancer Genomics With Accurate Long- and Short-Read Sequencing

Our ability to confidently detect somatic variants in cancer via DNA and RNA sequencing has been limited by the sequencing technologies currently used in cancer genomics. Accurate and comprehensive sequencing is required to characterize all types of somatic mutations, which includes not only small variants, but also structural variants, RNA isoforms, and fusions. In this seminar, you will learn how accurate long reads enable researchers to explore the complete genome and transcriptome, while highly accurate short reads lower the limit of detection for very rare variants in applications like liquid biopsy research.