Lab Management

Informatics

Standardization Efforts for AI

Program Committee Moderator(s)

• 

  Julie Hirschhorn, PhD (she/her/hers)

  System Director of Molecular Microbiology
  Geisinger
  Danville, Pennsylvania, United States

Co-Moderator (Early Career)(s)

• NS

  Nada Shaker, NS (she/her/hers)

  Surgical/bone and soft tissue fellow
  University of California San Francisco, UCSF
  San Francisco, California, United States

Session

Description: This session will explore the critical role of benchmarks and standards in the evolving landscape of clinical molecular diagnostics. We will delve into the work of the Genome in a Bottle Consortium, which develops benchmarks for human genome variant calling in normal and cancer samples, frequently used for training and testing variant callers, including AI-based approaches. Additionally, we will discuss how AI is revolutionizing clinical molecular diagnostics, emphasizing the importance of building consensus standards and enacting flexible but effective regulatory policies to ensure patient safety and ethical AI use. Join us to understand the interconnected processes of standard development and regulatory policy in advancing precision medicine.

Presentations:

• 2:30 PM – 3:15 PM PST

  Genome in a Bottle Benchmarks for Training and Testing AI-Based Variant Callers
  

  Breakout Speaker: Justin M. Zook, PhD (he/him/his) – NIST
• 3:15 PM – 4:00 PM PST

  Crafting the Blueprint: Standards Building and Policymaking for Clinical AI
  

  Breakout Speaker: Christina Silcox, PhD (she/her/hers) – Duke-Margolis Institute of Health Policy